Omre positions itself as a longevity-support brand, keeping its identity and formulations tied to cellular health and healthy aging support. The brand claims to tackle concerns often linked with aging, such as feeling tired, foggy, reduced bone density, or decreased strength.
The brand’s lineup features multiple offerings with anti-aging support benefits, which include compounds like NMN, resveratrol, and quercetin. However, are these offerings compatible with being included in your daily routine?
In this review, we cover the brand’s core background, range of offerings, transparency elements, associated advantages, and potential brand limitations.
About Omre
Founded by Dr. Pedram Kordrostami (MD, BSc, PGCert), Omre focuses on supporting cellular metabolism and delaying the effects of cellular aging through its longevity-focused offerings. The brand frames its purpose around the idea that cellular aging influences many age-related changes and that lifestyle factors such as stress and modern environmental exposures are potential contributors to aging.
The brand’s lineup is concise and clearly positioned around a few named formulas, with some signature offerings like Afterdrink®, NMN + Resveratrol, Spermidine, and Quercetin + Fisetin. Such a product catalog emphasizes research-backed dosing and bioavailability themes, with the manufacturers claiming to remove unnecessary or underdosed elements from the formulations.
As per its official website, all products are made in the USA in a GMP- and FDA-compliant or FDA-registered facility, and certificates of analysis are stated as available on product pages or by request. These products also undergo rigorous third-party lab testing to verify their potency, purity, and safety profile.
Omre Offerings
Spermidine
As per its official website, Spermidine is formulated to support cellular renewal processes by promoting autophagy, the body’s internal housekeeping function that helps cells break down dysfunctional proteins and recycle damaged cellular components. The formulation contains 1000mg of spermidine from wheat germ extract per two-capsule serving.
Spermidine is a naturally occurring polyamine that participates in cellular growth and repair signaling. It could promote autophagy by influencing cell signaling pathways that influence intracellular recycling, mitochondrial quality control, and protein turnover. By supporting these processes, spermidine may help the bodily cells maintain structural integrity and functional efficiency. Such effects might help delay age-related decline in cellular performance.
Quercetin + Fisetin
Quercetin + Fisetin is intended to help the body manage senescent cell burden, often referred to as zombie cells. Senescent cells are older, non-functioning cells that stop dividing normally but remain metabolically active and may release inflammatory signaling molecules into surrounding tissues. As their accumulation increases with age, the senescent-cell load contributes to chronic low-grade inflammation and reduced tissue regeneration capacity.
The formulation centers on the quercetin and fisetin flavonoids, which support antioxidant defense and cellular stress response modulation. Quercetin and fisetin act as senolytics through selective targeting of senescent cells by influencing survival pathways that keep these dysfunctional cells resistant to natural clearance. Such effects could promote improved cellular maintenance and reduce the inflammatory burden that may otherwise interfere with normal tissue function.
Quercetin in the formula may also influence oxidative stress reduction, endothelial function support, and inflammatory cytokine modulation. Meanwhile, fisetin has potential effects on neuroprotective signaling and inflammatory balance. Such effects might contribute to cognitive health and stress reduction.
NMN + Resveratrol
NMN + Resveratrol is formulated to support NAD+ restoration, energy metabolism, and age-related cellular resilience. The formulation uses NMN (nicotinamide mononucleotide) as its core ingredient, which works by targeting the restoration of NAD+ (nicotinamide adenine dinucleotide) levels that naturally decline with age. Such effects may support physical stamina, focus, and metabolic stability, with a specific focus on maintaining cellular performance.
The manufacturers added resveratrol to the formulation in a micronized trans-resveratrol form. Trans-resveratrol could support cellular stress adaptation and longevity-related signaling, largely due to its interaction with sirtuins, NAD+-dependent enzymes involved in regulating mitochondrial function, inflammation balance, and metabolic control. As sirtuin activity depends on NAD+ availability, pairing resveratrol with NMN creates a pathway-level support that may optimize cellular health and vitality.
NMN + Resveratrol also contains BioPerine® as an absorption enhancer, intended to increase the bioavailability of resveratrol. Piperine-containing extracts may influence intestinal transport processes and reduce the rapid metabolism of certain polyphenols, increasing the likelihood that meaningful concentrations of resveratrol reach systemic circulation.
Afterdrink
Afterdrink is formulated as a recovery formulation intended to support comfort by targeting more than dehydration alone. The product is positioned around the idea that rough mornings can also be driven by inflammatory stress, oxidative burden, nutrient depletion, and disrupted sleep rhythms following alcohol intake.
To address these overlapping mechanisms, Afterdrink pairs a broad multi-nutrient and botanical blend that features a mix of 21 vitamins, amino acids, and herbal extracts. Such nutrients are intended to support metabolic recovery processes that take place primarily in the liver while also supporting digestive comfort.
DHM (dihydromyricetin) is included in the formula for its ability to influence alcohol-related pathways by supporting enzymatic processing and reducing oxidative stress load generated during ethanol breakdown. As alcohol is metabolized, intermediate compounds such as acetaldehyde may increase reactive oxygen species and place a higher demand on antioxidant systems. DHM has antioxidant capacity and the potential to help maintain steadier cellular signaling during alcohol-related stress.
Milk thistle is also featured as part of the antioxidant and liver-support framework. It provides silymarin compounds that have hepatoprotective effects, largely due to their antioxidant activity and membrane-stabilizing effects in liver cells. Afterdrink further includes ginger to support digestive comfort, particularly nausea and stomach unease, through its bioactive gingerols and shogaols that interact with gastric motility and inflammatory signaling in the GI tract.
Afterdrink also emphasizes replenishment of depleted nutrients through a high-dose B-vitamin and mineral blend. Intake of alcohol may increase nutrient demand and often contributes to faster depletion of certain B vitamins due to increased metabolic throughput and impaired absorption. B vitamins function as coenzymes in energy metabolism, helping the body convert carbohydrates, fats, and amino acids into usable cellular energy while supporting methylation and neurotransmitter-related pathways that can influence alertness and mental clarity.
Omre Advantages
Physician-Founded Brand Origins
Omre was founded by Dr. Pedram Kordrostami, who is listed as CEO and Founder on the brand’s official website. He holds an M.D. with six years of clinical experience as an emergency physician, along with BSc and PGCert credentials. These qualifications confirm formal medical training and place the brand’s leadership in a clinical, evidence-oriented context rather than a lifestyle or influencer-driven one.
Physician leadership helps distinguish Omre in a crowded nutrition support space, often driven by marketing trends. The involvement of a medically trained founder supports greater credibility around formulation choices, composition accuracy, and quality standards. This positioning appears intended to reduce reliance on unsubstantiated claims and may be appealing if you value safety, evidence awareness, and long-term health considerations.
Longevity-Focused Brand Vision
Omre states that it targets biological aging at the cellular level rather than short-term functional needs. This focus separates the brand from general nutrition brands that cover many lifestyle categories.
The brand states that its identity relies on matching research-aligned ingredients and precise composition. Its messaging often references aging-related pathways such as NAD⁺ metabolism, cellular senescence, and cellular maintenance, which are widely discussed in longevity research. This focus signals disciplined product development, which could be critical if you prioritize long-term cellular health, aligning with evidence-based strategies over fleeting fitness or wellness trends.
Omre Limitations
Developing Market Presence
Omre was founded in 2016 as Omre Co Ltd, making it a relatively new brand in the supplement and longevity nutrition market. Many competing brands have been operating for decades, which could impact brand familiarity and long-term market credibility.
Due to the brand’s shorter history, it has had less time to build broad consumer recognition and validate its products at scale. There is also less multi-year user data, fewer long-term clinical studies, and a smaller volume of independent reviews. If you rely on long-term performance evidence, this developing market presence can make comparisons with established brands more difficult.
Online-First Brand Distribution
Omre sells its products only through its own website, omre.co. The brand uses a direct-to-consumer model and promotes subscriptions for repeat deliveries. There is no visible presence in health food stores or large retail chains. It may limit access to the brand’s offerings, especially if you prefer buying products in physical stores.
As the brand distributes fully online, variations may exist in shipping times and delivery reliability. Products are not available for same-day purchase or local pickup. All returns, changes, and support requests must go through online channels. The absence of retail placement also removes in-store product comparison and face-to-face guidance.
Pros
- Founded by Dr. Pedram Kordrostami, the brand’s formulations are based on clinical precision and trial data dosing.
- The brand claims adherence to third-party lab testing (twice) and manufacturing in GMP- and FDA-compliant facilities in the USA.
- Offerings may provide multiple benefits, such as reduced fatigue, better sleep, improved energy, and joint comfort.
- Provides a 30-day money-back guarantee on purchases.
Cons
- Limited product variety focuses narrowly on longevity support, with no broader vitamins or daily essentials.
- A few users experienced delays in shipments and refund processing.
Omre Alternatives
Tru Niagen
When comparing the brands, both Tru Niagen and Omre position themselves as longevity-oriented brands built around cellular health. However, the brands differ significantly in their scope of offerings, validation transparency, core positioning, and accessibility.
Credibility framing shows a contrast in how each brand builds trust. As per its official website, Tru Niagen leans heavily on quantified research scale indicators, stating it is backed by 25 years of research and innovation.
The brand also highlights 40+ human clinical studies, 50+ patents, 500+ published scientific studies, and 300+ global research collaborations. Meanwhile, Omre builds credibility primarily through founder authority and formulation philosophy, stating it was founded by Dr. Pedram Kordrostami (MD as CEO), positioning the brand as created by a doctor for his family.
Tru Niagen positions itself as a science-forward NAD+ support brand built around nicotinamide riboside, using Niagen as a patented and clinically studied precursor intended to raise NAD+ levels as they decline with age and lifestyle stressors. The brand organizes its offerings across categories like Foundational, Pro, Immune, and Beauty. Some core offerings include options like the Tru Niagen® 300mg, Tru Niagen® 150mg, Tru Niagen® Pro 1000mg, Tru Niagen® Beauty, and Tru Niagen® Immune. The brand also offers some bundled options under the Foundational, Immune, and Beauty categories. Meanwhile, Omre is positioned more broadly around longevity and healthspan support through a small set of longevity-themed formulations. As part of its product catalog, the brand offers products like the Spermidine, Quercetin + Fisetin, Afterdrink®, and NMN + Resveratrol.
Quality and traceability transparency are one of the strongest functional differentiators. Tru Niagen describes an unusually formal COA infrastructure, stating every bottle is fully traceable via a certificate of analysis. The brand describes its labs as ISO/IEC 17025:2017 accredited and claims at least 19 internal and third-party tests for product testing and release, including raw ingredient testing and finished product testing. It also adds manufacturing and assembly detail, stating products are blended, encapsulated, and bottled in the U.S. using globally sourced materials and referencing inspections by NSF Star K Kosher and IFANCA Halal.
Meanwhile, Omre frames quality more through dosing and batch testing principles, stating it avoids under-dosed formulas and trend-driven ingredients. The brand further claims its products are formulated, tested, and manufactured in the USA in a GMP and FDA-registered compliant facility. All its offerings undergo third-party testing twice, and COAs are available on product pages or by email request.
ProHealth
ProHealth and Omre both operate in the longevity-focused supplement space, built around supporting cellular health and healthspan themes. However, the brands differ in their brand heritage, catalog breadth, guidance model, and how each brand structures credibility and product selection.
Founded in 1988 by Rich Carson, ProHealth is presented as a longevity support brand and education platform based on the idea that biological aging can be addressed by targeting systems that slow with age. The brand also integrates a formal Medical Advisors section listing Dr. Richard Kaszynski as overseeing clinical research and Dr. Joseph Maroon emphasizing product contamination risks.
Meanwhile, Omre’s medical authority is primarily concentrated in its single founder identity through Dr. Pedram Kordrostami, MD. The brand’s narrative is focused on targeting lifestyle-driven chronic problems and the role of cellular aging in age-related decline rather than a larger advisory board structure.
In terms of product range, there are some differences between the brands. ProHealth maintains a diverse product ecosystem of 175+ offerings, which target age-related NAD+ decline, mitochondrial function, and cellular energy production. Some featured products from the brand include the NMN Pro 1000™, NMN Pro™ Powder, Calcium AKG Longevity, Trans Resveratrol Plus, TMG Pro Tablets, Berberine Pro, Fisetin Pro Longevity Plus, and Quercetin / Bromelain Complex. Beyond formulations, the brand also offers an at-home lab test kit called the TruMe Biological Age Test. Meanwhile, Omre’s lineup is intentionally narrow and longevity themed instead of offering multiple products across many systems. As part of its product ecosystem, the brand offers signature offerings such as Afterdrink®, NMN + Resveratrol, Spermidine, and Quercetin + Fisetin. Unlike ProHealth, the brand does not extend to biological test panels.
How Did We Evaluate?
Real Consumer Reviews
To evaluate Omre, we reviewed the Amazon review patterns across two core offerings from the brand to gain perspective into how these products performed in real-world use. Omre’s Afterdrink carries a 4.3 out of 5 score from 1,000+ reviews on Amazon. Many users described the formulations as noticeably reducing hangover intensity, especially those who were prone to hangovers. Several users highlighted that the product helped them wake up without grogginess, and some mentioned better sleep quality compared with typical drinking nights. However, a few users expressed dissatisfaction with the high capsule count (three before + three after), with some users describing it as inconvenient.
NMN + Resveratrol maintains a 4.1 out of 5 score on Amazon based on 35+ reviews. Consumers frequently praised the clean ingredients and the absence of common additives/fillers in the formula. Many users described noticeable energy improvements, especially morning alertness, workout performance, and fasting stamina. However, some users acknowledged that multiple lifestyle factors, such as diet, running, or reduced alcohol intake, could influence outcomes.
Based on the available feedback, it appears that most users appreciated the brand’s formulations, especially for reducing hangover-related aftereffects, improving energy levels, and reducing grogginess. However, critical feedback focused on the inconvenience with the dosage and the premium price positioning of the products.
Brand Credibility
While evaluating Omre, we assessed the brand’s ratings across independent review forums, operational consistency, and its core positioning. The brand positions its offerings around supporting longevity, cellular health, and vitality.
On TenereTeam, the brand holds a 4.5 out of 5 score based on a very limited number of reviews. Many users appreciated the brand’s offerings, such as NMN + Resveratrol and Spermidine, for supporting cellular NAD+ levels and daily vitality. Some users also praised the brand for its third-party testing standards, additive-free formulations, and convenience and consistency tied to tablet formats. However, a few users found the brand’s products comparatively more expensive than those from similar brands.
Across other platforms like Trustpilot and ThingTesting, the brand maintains no active presence, which could limit cross-platform verification. Due to this, our evaluation of the brand considers only TenereTeam as the primary reputation signal.
Frequently Asked Questions
No. The brand does not maintain an allergen-free statement or a comprehensive allergen disclosure for its formulations, such as NMN + Resveratrol and Spermidine. The brand mentions third-party testing and GMP/FDA-compliant manufacturing, but it does not clearly list whether products are free from common allergens such as gluten, soy, dairy, nuts, or shellfish.
Yes. The brand notes potential medication interactions, especially for NMN + Resveratrol. The makers indicate NMN may interact with medications for blood sugar, blood pressure, or chronic conditions. The brand also warns resveratrol may interact with blood thinners or NSAIDs, with possible bleeding or stomach upset concerns.
Not disclosed. The brand does not clearly label its full lineup as vegan or provide complete capsule/excipient disclosures. Some ingredients are plant-derived (e.g., spermidine from wheat germ extract), but that alone does not confirm vegan compliance. The brand does not consistently disclose capsule material (e.g., gelatin vs. cellulose) or confirm vegan certification, so vegan compatibility cannot be verified across all offerings.
Conclusion
Omre keeps its identity around supporting cellular vitality and longevity-focused themes. The brand emphasizes a doctor-led identity and frames quality through twice-performed third-party testing and USA-based manufacturing standards.
However, the brand’s lineup appears limited in scope as it does not include broader product categories such as vitamins, minerals, or general nutrition support, which can make long-term adherence to the brand’s offerings dependent on external stacking.
Safety and practicality considerations remain important because the brand’s positioning leans on complex longevity ingredients with limited long-term trials or peer-reviewed research to back the products. It is also important to note that personal experiences with the brand’s offerings might vary depending on your budget, metabolic health, genetics, frequency of use, and lifestyle factors.
- About the Author
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Alisha Matthew has been a practicing nutritionist since 2016. She holds a master’s degree in nutrition from the University of IOWA. She is a staunch believer in improving the human health index by educating people about nutrition and the importance of nutrition in leading a healthy and happy life. Her long-term goal is to keep educating people on general health and keep herself updated with the latest trends in the field of health.